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Experiment details for ins

Xenopus pax6 mutants affect eye development and other organ systems, and have phenotypic similarities to human aniridia pati...

Xenopus pax6 mutants affect eye development and other organ systems, and have phenotypic similarities to human aniridia patients.

Gene Clone Species Stages Anatomy
ins tropicalis NF stage 42 pancreas , ventral pancreatic bud

  Fig. 8. insulin (ins) expression is downregulated in pax6 mutants. Wild-type (left) and pax6 mutant (right) embryos at stage 42 were subjected to in situ hybridization with an ins probe. Expression of ins gene in this lateral view of mutant embryos (white arrows) is reduced compared to the level seen in wild-type embryos (orange arrows). (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)