Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Search Criteria
Gene/CloneSpeciesStageAnatomy ItemExperimenter
insxenopus   

Too many results?Too few results?

Experiment details for ins

Remodeling of insulin producing beta-cells during Xenopus laevis metamorphosis.

Remodeling of insulin producing beta-cells during Xenopus laevis metamorphosis.

Gene Clone Species Stages Anatomy
ins.S laevis NF stage 62 to NF stage 66 pancreas , islets of Langerhans

  Fig. 4. Insulin mRNA in situ hybridization of control and transgenic pancreases at varying stages. These reactions were carried out together and developed for the same time. (A) Control premetamorphic pancreas has small islets that stain for insulin mRNA with similar intensity as (D) adult islet cells. (B) At NF62 most of the insulin mRNA is down regulated and reexpression begins at (C) the end of climax NF66. The pInsulin-TRDN transgenic pancreas does not down regulate insulin mRNA at (E) NF62 or (F) NF66, but its ability to aggregate by NF66 is not impaired. (G) pElastase-TRDN-GFP at NF66 showed similar insulin mRNA down regulation as that of wild-type but the β-cells do not aggregate. Scale bar equals 40 μm.