|
Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
nkx2-5
|
|
laevis
|
NF stage 25
|
cardiac mesoderm
,
primary heart field
,
secondary heart field
|
vcan
|
|
laevis
|
NF stage 25
|
head region
,
mesoderm
,
presomitic mesoderm
,
cardiac mesoderm
,
cranial neural crest
,
[+]
|
has2
|
|
laevis
|
NF stage 25
|
head region
,
mesoderm
,
presomitic mesoderm
,
cardiac mesoderm
,
paraxial mesoderm
|
|
|
Figure 3. Developmental expression profiles and knockdown analysis of XHAPLN3 and Xhas2. A-D: Whole-mount in situ hybridization of Nkx2.5 (A), XHAPLN3 (B), Xversican (C), and Xhas2 (D). Lateral views are shown, with the anterior toward the left and dorsal side upward. The arrowhead indicates the precardiac mesoderm (PCM). E-G: The effects of depleting XHAPLN3 and Xhas2 are validated by the pattern of XcTnI expression. Normal tadpole heart structure (E, arrow). F,G: However, both XHAPLN3-morphant (F) and Xhas2-morphant (G) show no XcTnI expression. Ventral views are shown, with anterior upward. |
|
|
|
hapln3 (hyaluronan and proteoglycan link protein 3 ) gene expression in Xenopus laevis embryo, assayed via in situ hybridization, NF stage 25, lateral view, anterior left, dorsal up. |