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Fig. 2. fzd7 expression coincides with expression of the early heart markers nkx2-5,
tnnic and gata6. Lateral view of Xenopus laevis embryos at stage 31 showing fzd7
expression detected in red (A-Aii) and co-localised by double in situ hybridisation with
other heart markers in dark blue including nkx2-5 (B-Bii), tnnic (C-Cii) and gata6 (DDii).
(Ai, Bi, Ci, Di). Magnified lateral view of the same embryos in (A, B, C and D)
respectively. (Aii, Bii, Cii, Dii). Cross section through the heart region of the embryos
in (A, B, C, D) respectively. fzd7 is expressed in the myocardium and pericardium (Aii)
and in other structures including neural crest, eye, pronephric duct and tail bud. fzd7
expression shows a high degree of overlapping with the heart markers in the
myocardium but not in the pericardium (Bii, Cii, Dii). h: heart, c: cement gland, e: eye,
nc: neural crest, pnd: pronephric duct, tb: tail bud, mc: myodcardium, lpm: lateral plate of mesoderm. Magnification: 20x in (A, B, C, D), 30x in (Ai, Bi, Ci, Di), 200x in (Aii, Bii,
Cii, Dii). |
