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foxa1xenopus   

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Experiment details for foxa1

Combined ectopic expression of Pdx1 and Ptf1a/p48 results in the stable conversion of posterior endoderm into endocrine and ...

Combined ectopic expression of Pdx1 and Ptf1a/p48 results in the stable conversion of posterior endoderm into endocrine and exocrine pancreatic tissue.

Gene Clone Species Stages Anatomy
foxa1.L laevis NF stage 41 cloaca , dorsal pancreatic bud , ventral pancreatic bud

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  Fig. S5. Loss of pancreatic tissue in Ptf1a/p48 MO injected embryos does not result in an obvious increase of duodenum and intestine marker gene expression. No obvious difference was observed in the expression of Cyl18 in a comparison of Ptf1a/p48 MO injected and uninjected control embryos (1 and 2). Ptf1a/p48 MO injected embryos, that display a loss of the pancreatic buds, reveal no significant change of Foxa1 expression, except for a slight anterior shift into presumptive stomach and duodenum (panel 4, 59%, n= 22).