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Figure 4. Fgfr4 expression during early X. tropicalis development, detected by in situ hybridization. (A,B) Whole stage 19 embryos; expression is detected in the head region (2: eyes), lateral plate mesoderm (3), anterior somites (1a) and posterior pre-somitic mesoderm (1b). (C,D) Transcripts were not detected in stage 16 and 19 GRPs (arrowheads). (E,F) Stage 10.5 embryos, whole (E, dorsal view) or bisected through the dorsal midline (F); fgfr4 is broadly expressed in the ectoderm (4) and dorsal marginal zone (5). (G,H) Stage 12 embryos, whole (G, dorso-vegetal view) or bisected (H); fgfr4 is absent from the marginal zone (5), but is expressed in the anterior migrating involuted mesoderm (6). |
