|
Gene |
Clone |
Species |
Stages |
Anatomy |
fgf8.L
|
|
laevis
|
NF stage 10
|
marginal zone
,
blastopore lip
,
axial mesoderm
|
fgf8.L
|
|
laevis
|
NF stage 20
|
diencephalon
,
midbrain-hindbrain boundary
,
central nervous system
,
neural plate
,
cranial neural crest
,
[+]
|
fgf8.L
|
|
laevis
|
NF stage 29 and 30
|
brain
,
forebrain
,
diencephalon
,
midbrain-hindbrain boundary
,
stomodeal-hypophyseal primordium
,
[+]
|
Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
ism1
|
|
laevis
|
NF stage 10
|
ventro-lateral marginal zone
,
lower blastopore lip
|
ism1
|
|
laevis
|
NF stage 17
|
neuroectoderm
,
neural groove
,
anterior neural fold
|
ism1
|
|
laevis
|
NF stage 20
|
midbrain-hindbrain boundary
,
pre-chordal neural plate
,
cranial neural crest
|
ism1
|
|
laevis
|
NF stage 29 and 30
|
otic vesicle
,
brain
,
forebrain
,
diencephalon
,
midbrain-hindbrain boundary
,
[+]
|
ism1
|
|
laevis
|
NF stage 17
|
neuroectoderm
,
notochord
,
neural plate
,
anterior neural fold
,
anterior
|
|
|
Fig. 3. Comparison of xIsm and xFgf-8 expression. (A,D) Stage 10 embryos in vegetal view; note that xIsm and xFgf-8 expression overlap in the ventrolateral blastopore lip (vbl). (B,E) Stage 17 embryos in dorso-vegetal view showing expression of xIsm and xFgf-8 in the anterior notochord (n). (C,F) Stage 20 embryos in anterior view; note overlapping expression of xIsm and xFgf-8 in cranial neural crest (nc), anterior edge of neural plate (anp), and midbrain–hindbrain border (arrowheads). (G–I) Stage 30 embryos in lateral view. (G) Whole-mount in situ hybridization depicting xIsm expression in the branchial arches (ba), diencephalon (di), ear placode (e), and isthmus (arrowhead). (H) xFgf-8 expression at the same stage. (I) Double in situ hybridization of xIsm and xFgf-8; note the overlap of expression in branchial arches, diencephalon and isthmus (arrowhead), as well as the complementary expression in the ear placode. |