Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Search Criteria
Gene/CloneSpeciesStageAnatomy ItemExperimenter
actc1xenopus   

Too many results?Too few results?

Experiment details for actc1

Leiomodin 3 and tropomodulin 4 have overlapping functions during skeletal myofibrillogenesis.

Leiomodin 3 and tropomodulin 4 have overlapping functions during skeletal myofibrillogenesis.

Gene Clone Species Stages Anatomy
actc1.L laevis NF stage 15 presomitic mesoderm , paraxial mesoderm

Display additional annotations [+]
  Fig. S1. Developmental expression of Tmod and Lmod family proteins at the neurula stage prior to skeletal muscle assembly. Tmod (B-D) and Lmod (E-H) family gene expression was analyzed using in situ hybridization. All embryos are positioned with heads to the left. Expression patterns were analyzed at the neurula stage (st15), before the onset of myofibrillogenesis. Expression of the striated muscle marker, cardiac actin, actna1 (A) was used to indicate skeletal muscle tissue in the embryo. Arrows indicate developing skeletal muscle in the somites. Only lmod3 (D) and tmod4 (H) are expressed at high levels in developing skeletal muscle.

Gene Clone Species Stages Anatomy
actc1.L laevis NF stage 15 presomitic mesoderm , paraxial mesoderm

  actc1 (actin, alpha, cardiac muscle 1) gene expression in Xenopus laevis embryo, assayed via in situ hybridization, NF stage 15, lateral view, anterior left, dorsal up.

Gene Clone Species Stages Anatomy
actc1.L laevis NF stage 29 and 30 presomitic mesoderm , somite , heart , muscle , epaxial muscle

Display additional annotations [+]
  Fig. 1. Structure and developmental expression of the leiomodin (Lmod) and tropomodulin (Tmod) gene families. (A) leiomodin (Lmod1–3) and tropomodulin (Tmod1–4) proteins are structurally related, yet possess unique domains. Lmods and Tmods share actin-binding (A1, A2), tropomyosin-binding (TM1) and leucine-rich-repeat (LRR) domains. A second tropomyosin-binding domain (TM2) is unique to the Tmods. Lmod proteins have a Cterminal extension that contains a third actin binding/WH2 domain (WH2/A3). (B–I) Lmod (C–E) and Tmod (F–I) family gene expression was analyzed during Xenopus embryonic development using in situ hybridization. All embryos are positioned with heads to the left. Expression patterns are shown at the early tailbud stage (st30), during the early stages of myofibrillogenesis. Earlier expression during the neurula stage (st15) is presented in supplementary material Fig. S1. Expression of the definitive striated muscle marker cardiac actin, actna1 (B), was used to indicate cardiac and skeletal muscle tissue in the embryo. Arrows indicate developing skeletal muscle and heart tissues. Only lmod3 (E) and tmod4 (I) are expressed at high levels in developing skeletal muscle.

Gene Clone Species Stages Anatomy
actc1.L laevis NF stage 33 and 34 presomitic mesoderm , somite , heart , muscle , epaxial muscle

  actc1 (actin, alpha, cardiac muscle 1) gene expression in Xenopus laevis embryo, assayed via in situ hybridization, NF stage 34, lateral view, anterior left, dorsal up.