Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Plays a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice...[+]

Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Plays a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD