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Summary Expression Phenotypes Gene Literature (21) GO Terms (10) Nucleotides (81) Proteins (40) Interactants (471) Wiki
Gene Symbol:

Gene Name: 
R-spondin 2

CRISTIN2 , R-spondin 2 ( Nomenclature history )

Gene Function:
Subtilisin-like proprotein convertase

Protein Function :
Activator of the canonical Wnt signaling pathway by acting as a ligand for lgr4-6 receptors. Upon binding to lgr4-6 (lgr4, lgr5 or lgr6), lgr4-6 associate with phosphorylated lrp6 and frizzled receptor...[+]

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Disease Ontology:
tetraamelia syndrome 2

External Links:
Expression                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info