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Summary Expression Phenotypes Gene Literature (120) GO Terms (7) Nucleotides (156) Proteins (52) Interactants (636) Wiki
XB-GENEPAGE-481819
Gene Symbol:
 lrp6

Gene Name: 
LDL receptor related protein 6

Synonyms:
adcad2 , LOC108712563 , lrp6-a , lrp6-b , Xlrp6 [-] ( Nomenclature history )

Gene Function:
signal transduction

Protein Function :
Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes.


InterPro :
LDLR classB rpt, LDL receptor-like sf, LDLR class-A CS, EGF-like dom, [+]

Interactants:
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Diseases: 


Disease Ontology:
tooth agenesis [+]

External Links:
 
Expression                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info