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Summary Expression Phenotypes Gene Literature (43) GO Terms (16) Nucleotides (108) Proteins (51) Interactants (517) Wiki
XB-GENEPAGE-486780
Gene Symbol:
 axin1

Gene Name: 
axin 1

Synonyms:
axin , fused , xAxin ( Nomenclature history )

Gene Function:
negative regulator of the wnt signaling pathway

Protein Function :
Component of the beta-catenin destruction complex required for regulating ctnnb1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via tw...[+]


InterPro :
Axin-like, Axin b-cat-bd, Axin TNKS-bd, DIX, [+]

Interactants:
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Diseases: 


Disease Ontology:
hepatocellular carcinoma

External Links:
 
Expression                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info