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Summary Expression Phenotypes Gene Literature (6) GO Terms (12) Nucleotides (219) Proteins (59) Interactants (117) Wiki
XB-GENEPAGE-481915
???displayGene.symbol???:
 psen1

???displayGene.name???: 
presenilin 1

???displayGene.synonyms???
X-PS-alpha , X-PS-beta ( Nomenclature history )

???displayGene.geneFunction???
intracellular signaling

Protein Function :
Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.


InterPro :
Preselin/SPP, Presenilin C, Peptidase A22A, Znf-3CxxC, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
Alzheimer's disease 3 [+]

External Links:
 
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info