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Summary Expression Expr. PhenotypesPheno. Gene Literature (0)Lit. (0) GO Terms (79)GO (79) Nucleotides (124)Nucl. (124) Proteins (51)Prot. (51) Interactants (52)Interact. (52) Wiki
XB-GENEPAGE-967320
???displayGene.symbol???:
 eif2ak4

???displayGene.name???: 
eukaryotic translation initiation factor 2 alpha kinase 4

???displayGene.synonyms???
LOC108699198 ( Nomenclature history )

???displayGene.geneFunction???
eIF-2alpha kinase GCN2

AI Protein Function :
eif2ak4 encodes a serine/threonine‑protein kinase that phosphorylates eIF2α in response to amino‑acid deprivation and oxidative stress, thereby reducing global translation initiation. The kinase acts a...[+]


InterPro :
Protein kinase ATP BS, Ser/Thr kinase AS, Kinase-like dom sf, Prot kinase dom, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
pulmonary venoocclusive disease [+]

MIM:
PULMONARY VENOOCCLUSIVE DISEASE 2, AUTOSOMAL RECESSIVE; PVOD2

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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