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Summary Expression Phenotypes Gene Literature (0) GO Terms (12) Nucleotides (50) Proteins (32) Interactants (12) Wiki
XB-GENEPAGE-984100
???displayGene.symbol???:
 edaradd

???displayGene.name???: 
EDAR associated via death domain

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crinkled , LOC108717806 ( Nomenclature history )

???displayGene.geneFunction???
Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways

AI Protein Function :
The gene edaradd encodes an adaptor protein involved in the ectodysplasin signaling pathway. It mediates NF-kB activation downstream of the EDAR receptor. The protein is cytoplasmic and its function is...[+]


InterPro :
DEATH-like dom sf, Death domain, EDARADD

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Diseases: 


Disease Ontology:
tooth agenesis [+]

MIM:
ECTODERMAL DYSPLASIA 10A, HYPOHIDROTIC/HAIR/NAIL TYPE, AUTOSOMAL DOMINANT; ECTD1 [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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