The dlg5 protein is a membrane-associated guanylate kinase (MAGUK) scaffold protein containing PDZ domains that localizes to apical junctional complexes in epithelial cells. It plays a role in maintain...[+]

The dlg5 protein is a membrane-associated guanylate kinase (MAGUK) scaffold protein containing PDZ domains that localizes to apical junctional complexes in epithelial cells. It plays a role in maintaining cell polarity during embryonic development, particularly in the neural tube and retina. Expression is also detected in the otic vesicle, branchial arches, and pronephros. [-]

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