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Summary Expression Phenotypes Gene Literature (3) GO Terms (48) Nucleotides (323) Proteins (99) Interactants (230) Wiki
XB-GENEPAGE-957702
???displayGene.symbol???:
 huwe1

???displayGene.name???: 
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1

???displayGene.synonyms???
LOC108699996 , LOC108704466 ( Nomenclature history )

???displayGene.geneFunction???
ubiquitin-protein ligase

AI Protein Function :
The huwe1 protein is an e3 ubiquitin-protein ligase involved in the ubiquitination process, targeting proteins for proteasomal degradation during embryonic development. It regulates cell proliferation ...[+]


InterPro :
E3 Ub ligase DUF908, ARM-type fold, E3 Ub ligase DUF913, E3 ubiq-protein ligase, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
syndromic X-linked intellectual disability type 10 [+]

MIM:
HSD10 MITOCHONDRIAL DISEASE; HSD10MD [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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