The gene tomm22 in Xenopus laevis and Xenopus tropicalis encodes a mitochondrial import receptor protein that is a core component of the translocase of the outer mitochondrial membrane. It facilitates ...[+]

The gene tomm22 in Xenopus laevis and Xenopus tropicalis encodes a mitochondrial import receptor protein that is a core component of the translocase of the outer mitochondrial membrane. It facilitates the import of nuclear-encoded mitochondrial proteins into the mitochondria, playing a critical role in mitochondrial biogenesis and function. The protein is localized to the mitochondrial outer membrane and is essential for mitochondrial protein import and overall mitochondrial function. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD