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Summary ExpressionExpr. PhenotypesPheno. Gene Literature (8)Lit. (8) GO Terms (36)GO (36) Nucleotides (405)Nucl. (405) Proteins (80)Prot. (80) Interactants (341)Interact. (341) Wiki
XB-GENEPAGE-943467
???displayGene.symbol???:
 kars1

???displayGene.name???: 
lysyl-tRNA synthetase 1

???displayGene.synonyms???
kars , kars2 , krs ( Nomenclature history )

???displayGene.geneFunction???
Lysyl-tRNA synthetase (class II)

AI Protein Function :
kars1 encodes a cytoplasmic lysyl‑tRNA synthetase that catalyzes the ATP‑dependent ligation of lysine to its cognate tRNA, enabling translation elongation. The protein localizes to the cytoplasm and pa...[+]


InterPro :
Lys-tRNA-ligase II bac/euk, Lys-tRNA-ligase II, NA-bd OB tRNA, aa-tRNA-synth II, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
autosomal recessive nonsyndromic deafness [+]

MIM:
CHARCOT-MARIE-TOOTH DISEASE, RECESSIVE INTERMEDIATE B; CMTRIB [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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