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Summary Expression Phenotypes Gene Literature (239) GO Terms (245) Nucleotides (370) Proteins (50) Interactants (1869) Wiki
XB-GENEPAGE-484285
???displayGene.symbol???:
 tp53

???displayGene.name???: 
tumor protein p53

???displayGene.synonyms???
p53 , Trp248 , tumor suppressor p53 , Xp53 , Xrel3 [-] ( Nomenclature history )

???displayGene.geneFunction???
transcription factor regulating cell cycle, apoptosis and TGF-beta signaling

AI Protein Function :
The tp53 gene encodes a transcription factor with tumor suppressor functions localized to the nucleus. It is activated in response to DNA damage, inducing cell cycle arrest through transcriptional upre...[+]


InterPro :
p53 DNA-bd, p53/RUNT-type TF DNA-bd sf, p53 tetramer sf, p53 tetrameristn, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
chronic lymphocytic leukemia [+]

MIM:
HEPATOCELLULAR CARCINOMA [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:
???displayGene.mophenotype???
???displayGene.mosmith??? tneu034a23      


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