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Summary Expression Phenotypes Gene Literature (15) GO Terms (25) Nucleotides (87) Proteins (46) Interactants (123) Wiki
XB-GENEPAGE-481464
???displayGene.symbol???:
 kremen1

???displayGene.name???: 
kringle containing transmembrane protein 1

???displayGene.synonyms???
kremen , kremen 1 , krm1 ( Nomenclature history )

???displayGene.geneFunction???
dickkopf receptor

AI Protein Function :
Kremen1 is a transmembrane receptor that acts as a wnt signaling pathway inhibitor by forming a ternary complex with dkk1 and lrp6 to promote internalization of the wnt receptor complex. It is expresse...[+]


InterPro :
Sperma CUB dom sf, CUB dom, WSC carb-bd, Kremen rcpt, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
ectodermal dysplasia 13

MIM:
ECTODERMAL DYSPLASIA 13, HAIR/TOOTH TYPE; ECTD13

External Links:
 
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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