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Summary Expression Phenotypes Gene Literature (21) GO Terms (182) Nucleotides (186) Proteins (57) Interactants (702) Wiki
XB-GENEPAGE-480854
???displayGene.symbol???:
 apc

???displayGene.name???: 
adenomatous polyposis coli

???displayGene.synonyms???
xapc ( Nomenclature history )

???displayGene.geneFunction???
tumor suppressor

AI Protein Function :
The apc protein functions as a negative regulator of the Wnt signaling pathway, acting as a scaffold protein in the destruction complex that targets β-catenin for degradation. It localizes to the nucle...[+]


InterPro :
Armadillo, APC N, Apc fam, APC 15aa rpt, [+]

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Diseases: 


Disease Ontology:
familial adenomatous polyposis [+]

MIM:
MEDULLOBLASTOMA; MDB [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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