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Summary Expression Expr. PhenotypesPheno. Gene Literature (33)Lit. (33) GO Terms (38)GO (38) Nucleotides (88)Nucl. (88) Proteins (41)Prot. (41) Interactants (441)Interact. (441) Wiki
XB-GENEPAGE-478209
???displayGene.symbol???:
 fzd4

???displayGene.name???: 
frizzled class receptor 4

???displayGene.synonyms???
frizzled 4 , frizzled-4 , frizzled4 , Fz-4 , Fz4 , LOC108708760 [+] ( Nomenclature history )

???displayGene.geneFunction???
transmembrane receptor in the wnt signaling pathway

AI Protein Function :
fzd4 is a membrane bound Frizzled class receptor that functions as a Wnt signaling component, activating canonical β‑catenin pathway. It regulates eye morphogenesis, neural tube patterning, somite form...[+]


InterPro :
Frizzled dom sf, Frizzled/Smoothened TM, Frizzled dom, FZ4 CRD, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
exudative vitreoretinopathy [+]

MIM:
EXUDATIVE VITREORETINOPATHY 1; EVR1

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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