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Summary Expression Expr. PhenotypesPheno. Gene Literature (150)Lit. (150) GO Terms (126)GO (126) Nucleotides (233)Nucl. (233) Proteins (55)Prot. (55) Interactants (988)Interact. (988) Wiki
XB-GENEPAGE-485690
???displayGene.symbol???:
 smad4

???displayGene.name???: 
SMAD family member 4

???displayGene.synonyms???
dpc4 , jip , madh4 , smad4.1 , smad4a , smad4alpha [+] ( Nomenclature history )

???displayGene.geneFunction???
signal transduction, tgf-beta pathway

AI Protein Function :
smad4 is a co‑Smad transcriptional co‑factor that mediates TGF‑β, activin and BMP signals by forming complexes with receptor‑regulated Smads and translocating to the nucleus to regulate target gene exp...[+]


InterPro :
SMAD FHA dom sf, Dwarfin, MAD homology1 Dwarfin-type, MAD homology MH1, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
juvenile polyposis syndrome [+]

MIM:
PANCREATIC CANCER [+]

External Links:
1/3
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:
???displayGene.mophenotype???
???displayGene.mosmith??? tneu052c18      


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