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Summary Expression Expr. PhenotypesPheno. Gene Literature (17)Lit. (17) GO Terms (27)GO (27) Nucleotides (433)Nucl. (433) Proteins (116)Prot. (116) Interactants (296)Interact. (296) Wiki
XB-GENEPAGE-957447
???displayGene.symbol???:
 impdh1

???displayGene.name???: 
inosine monophosphate dehydrogenase 1

???displayGene.synonyms???
imp2 , IMPD , IMPD1 , IMPDH-I , LCA11 , LOC108713018 [+] ( Nomenclature history )

???displayGene.geneFunction???
IMP dehydrogenase/GMP reductase

AI Protein Function :
impdh1 encodes a cytosolic inosine‑monophosphate dehydrogenase that catalyzes the NAD⁺‑dependent oxidation of inosine‑5′‑monophosphate to xanthosine‑5′‑monophosphate, the rate‑limiting step in de novo ...[+]


InterPro :
Aldolase TIM, CBS dom, IMP DH, IMP DH GMPRt, [+]

???displayGene.geneInteractants???
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Diseases: 


Disease Ontology:
Leber congenital amaurosis 11 [+]

MIM:
RETINITIS PIGMENTOSA 10; RP10 [+]

External Links:
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???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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