Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (56) GO Terms (36) Nucleotides (228) Proteins (123) Interactants (906) Wiki
XB-GENEPAGE-1011627
???displayGene.symbol???:
 tcf4

???displayGene.name???: 
transcription factor 4

???displayGene.synonyms???
tcf-4 , Xtcf-4 , Xtcf4 ( Nomenclature history )

???displayGene.geneFunction???
helix-loop-helix (bHLH) transcription factor

AI Protein Function :
The tcf4 gene encodes a transcription factor belonging to the TCF/LEF family of HMG-box DNA-binding proteins. It acts as a nuclear effector for Wnt/β-catenin signaling, where it binds to DNA and recrui...[+]


InterPro :
HLH DNA-bd sf, bHLH dom, NeuroDiff E-box TFs

???displayGene.geneInteractants???
Loading ...

Diseases: 


Disease Ontology:
autosomal dominant intellectual developmental disorder [+]

MIM:
PITT-HOPKINS SYNDROME; PTHS [+]

External Links:
1/5
 
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info