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Summary Expression Phenotypes Gene Literature (92) GO Terms (5) Nucleotides (163) Proteins (37) Interactants (526) Wiki
XB-GENEPAGE-479959
Gene Symbol:
 casp3.2

Gene Name: 
caspase 3, gene 2

Synonyms:
Apopain , CASP-3 , caspase 3 , caspase-3 , xCPP32 [-] ( Nomenclature history )

Gene Function:
apoptotic cysteine protease

Protein Function :
Important mediator of apoptosis. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond.


InterPro :
Sec7 dom, Sec7 dom sf, Sec7 C sf, PH-like dom sf, [+]

Interactants:
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Diseases: 


External Links:
 
Expression                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info