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Summary Expression Phenotypes Gene Literature (51) GO Terms (9) Nucleotides (108) Proteins (45) Interactants (445) Wiki
XB-GENEPAGE-485116
Gene Symbol:
 lrp5

Gene Name: 
LDL receptor related protein 5

Synonyms:
bmnd1 , evr1 , evr4 , hbm , lr3 , lrp7 [+] ( Nomenclature history )

Gene Function:
Low-density lipoprotein receptors containing Ca2+-binding EGF-like domains

Protein Function :
Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes.


InterPro :
LDLR classB rpt, LDL receptor-like sf, LDLR class-A CS, LDrepeatLR classA rpt, [+]

Interactants:
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Diseases: 


Disease Ontology:
exudative vitreoretinopathy [+]

OMIM:
OSTEOPOROSIS [+]

External Links:
 
Expression                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info