ssbp3 Phenotypes

Phenotypes

XB-GENEPAGE-998010

Gene Symbol: ssbp3 Gene Name: single stranded DNA binding protein 3

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
duplicated main body axis (6 sources), duplicated head (5 sources), absent head (3 sources), duplicated eye (2 sources)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: ssbp3 manipulated (1 source)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + tle1 + gsc + otx2 + ssbp3 + ldb1 + lhx1 mRNA (3 sources), Xla Wt + gsc + ssbp3 + tle1 + lhx1 mRNA 5 (1 source), Xla Wt + otx2 + ssbp3 + ldb1 + lhx1 (1 source), Xla Wt + otx2 + ssbp3 + ldb1 + lhx1 mRNA (1 source), Xtr Wt + ssbp3 + ldb1 + lhx1 mRNA (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (32 sources): abnormal anterior head development, abnormal brain development, abnormal cephalic neural fold morphology, abnormal cranium morphology, abnormal embryo development, abnormal embryonic growth/weight/body size, abnormal forebrain development, abnormal head development, abnormal midbrain development, abnormal midbrain-hindbrain boundary development, abnormal neural plate morphology, abnormal somite development, abnormal somite shape, abnormal sternum morphology, abnormal telencephalon development, abnormal vertebral body morphology, absent diencephalon, absent forebrain, absent prechordal plate, asymmetric sternocostal joints, decreased cell proliferation, decreased embryo size, decreased midbrain size, decreased somite size, decreased sternebra number, embryonic lethality during organogenesis, incomplete penetrance, increased apoptosis, kinked neural tube, lethality throughout fetal growth and development, incomplete penetrance, no abnormal phenotype detected, prenatal lethality, complete penetrance, short tail [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (32 sources): abnormal anterior head development, abnormal brain development, abnormal cephalic neural fold morphology, abnormal cranium morphology, abnormal embryo development, abnormal embryonic growth/weight/body size, abnormal forebrain development, abnormal head development, abnormal midbrain development, abnormal midbrain-hindbrain boundary development, [+]