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Summary Expression Phenotypes Gene Literature (140) GO Terms (0) Nucleotides (27) Proteins (24) Interactants (246) Wiki
XB-GENEPAGE-996922

abcc8     ATP binding cassette subfamily C member 8

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: abcc8 assayed (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (107 sources): Abnormal C-peptide level, Abnormal brain FDG positron emission tomography, Abnormal circulating fatty-acid concentration, Abnormal heart morphology, Abnormal insulin level, Abnormal oral glucose tolerance, Abnormality of the ear, Abnormality of the genitourinary system, Abnormality of the immune system, Abnormality of the kidney, [+]
Mouse (9 sources): abnormal grip strength, abnormal insulin secretion, abnormal pancreatic beta cell morphology, decreased circulating glucose level, decreased insulin secretion, homeostasis/metabolism phenotype, increased circulating glucose level, increased insulin secretion, increased lean body mass

View all ortholog results at Monarch