| Monarch Ortholog Phenotypes
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Human (16 sources):
Abnormal auditory evoked potentials,
Abnormality of the hand,
Abnormality of visual evoked potentials,
Areflexia,
Axonal loss,
Decreased nerve conduction velocity,
Distal amyotrophy,
Distal muscle weakness,
Distal sensory impairment,
Gait disturbance,
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Mouse (12 sources):
abnormal fasting circulating glucose level,
abnormal grip strength,
abnormal lean body mass,
decreased body size,
decreased fasting circulating glucose level,
decreased grip strength,
hindlimb paralysis,
increased lean body mass,
limb grasping,
peripheral nervous system degeneration,
[+]
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.