abnormal memory B cell number, abnormal professional antigen presenting cell physiology, abnormal spleen B cell follicle morphology, abnormal splenic cell ratio, absent vibrissae, decreased B cell proliferation, decreased B-1 B cell number, decreased CD4-positive, alpha beta T cell number, decreased IgG1 level, decreased IgG2a level, decreased IgG2b level, decreased IgG3 level, decreased T cell proliferation, decreased alpha-beta T cell number, decreased apoptosis, decreased bone marrow cell number, decreased central memory CD4-positive, alpha-beta T cell number, decreased cytotoxic T cell cytolysis, decreased effector memory CD4-positive, alpha-beta T cell number, decreased eosinophil cell number, decreased response to antigen, decreased spleen germinal center number, decreased susceptibility to autoimmune diabetes, decreased susceptibility to experimental autoimmune encephalomyelitis, decreased susceptibility to parasitic infection, dermatitis, enlarged lymph nodes, immune system phenotype, impaired hematopoiesis, impaired humoral immune response, impaired macrophage chemotaxis, increased CD4-positive, alpha beta T cell number, increased CD8-positive, alpha-beta T cell number, increased IgG2a level, increased effector memory CD4-positive, alpha-beta T cell number, increased neuron apoptosis, no abnormal phenotype detected, premature death, respiratory system phenotype