insm1 Phenotypes

Phenotypes

XB-GENEPAGE-993148

Gene Symbol: insm1 Gene Name: insulinoma associated 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: insm1 manipulated (1 source)
Computed annotations: insm1 assayed (7 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + neurog3-GR + insm1 MO + DEX (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (32 sources): abnormal endocrine pancreas development, abnormal endocrine pancreas morphology, abnormal enteroendocrine cell morphology, abnormal neuron differentiation, abnormal olfactory epithelium morphology, abnormal pancreatic endocrine progenitor cell physiology, abnormal pituitary gland development, absent PP cells, absent somatotrophs, absent thyrotrophs, decreased adrenocorticotropin level, decreased follicle stimulating hormone level, decreased growth hormone level, decreased luteinizing hormone level, decreased neuron number, decreased pancreatic alpha cell number, decreased pancreatic delta cell number, decreased pancreatic endocrine progenitor cell proliferation, decreased pancreatic epsilon cell number, decreased pituitary hormone level, decreased prolactin level, decreased thyroid-stimulating hormone level, embryonic lethality during organogenesis, incomplete penetrance, increased PP cell number, increased neuron apoptosis, increased pancreas apoptosis, lethality throughout fetal growth and development, lethality throughout fetal growth and development, complete penetrance, lethality, complete penetrance, neonatal lethality, complete penetrance, pancreatic islet hypoplasia, perinatal lethality, incomplete penetrance [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (32 sources): abnormal endocrine pancreas development, abnormal endocrine pancreas morphology, abnormal enteroendocrine cell morphology, abnormal neuron differentiation, abnormal olfactory epithelium morphology, abnormal pancreatic endocrine progenitor cell physiology, abnormal pituitary gland development, absent PP cells, absent somatotrophs, absent thyrotrophs, [+]