Decreased serum testosterone concentration, Decreased testicular size, Delayed puberty, Diabetes mellitus, Emotional lability, Gynecomastia, Hypergonadotropic hypogonadism, Hyperinsulinemia, Hypertriglyceridemia, Hypoplasia of the ovary, Immune dysregulation, Insulin-resistant diabetes mellitus, Obesity, Orthostatic hypotension due to autonomic dysfunction, Pituitary hypothyroidism, Polyphagia, Primary amenorrhea, Recurrent upper respiratory tract infections, Short stature

abnormal body temperature, abnormal bone mineralization, abnormal chemokine level, abnormal circadian temperature homeostasis, abnormal circulating alanine transaminase level, abnormal circulating alkaline phosphatase level, abnormal circulating aspartate transaminase level, abnormal circulating bilirubin level, abnormal circulating calcium level, abnormal circulating chloride level, abnormal circulating cholesterol level, abnormal circulating fructosamine level, abnormal circulating iron level, abnormal circulating lipid level, abnormal circulating phosphate level, abnormal circulating potassium level, abnormal circulating total protein level, abnormal conditioned taste aversion behavior, abnormal diestrus, abnormal endometrium morphology, abnormal epididymal fat pad morphology, abnormal estrous cycle, abnormal exocrine pancreas morphology, abnormal exploration in a new environment, abnormal eye electrophysiology, abnormal fat pad morphology, abnormal female reproductive system morphology, abnormal food intake, abnormal functional residual capacity, abnormal gluconeogenesis, abnormal gonadal fat pad morphology, abnormal heart weight, abnormal hematocrit, abnormal hemoglobin content, abnormal hormone level, abnormal inhibitory postsynaptic currents, abnormal insulin secretion, abnormal interleukin level, abnormal intestinal epithelium morphology, abnormal kidney morphology, abnormal kidney papilla morphology, abnormal lactation, abnormal lean body mass, abnormal learning/memory/conditioning, abnormal lipid level, abnormal locomotor activation, abnormal locomotor behavior, abnormal locomotor circadian rhythm, abnormal lung compliance, abnormal mesenteric fat pad morphology, abnormal metestrus, abnormal myelin sheath morphology, abnormal myocardial fiber morphology, abnormal myocardium layer morphology, abnormal neuron physiology, abnormal nucleotide metabolism, abnormal osteoclast differentiation, abnormal oxygen consumption, abnormal pancreatic beta cell morphology, abnormal pancreatic beta cell physiology, abnormal pancreatic islet morphology, abnormal percent body fat/body weight, abnormal renal fat pad morphology, abnormal renal glomerulus morphology, abnormal respiratory electron transport chain, abnormal respiratory mechanics, abnormal response to cardiac infarction, abnormal response/metabolism to endogenous compounds, abnormal skeleton development, abnormal spatial learning, abnormal spatial reference memory, abnormal spleen weight, abnormal sympathetic nervous system physiology, abnormal synaptic dopamine release, abnormal uterus morphology, abnormal vascular development, abnormal vascular wound healing, abnormal white adipose tissue morphology, absent adrenal medulla, absent estrous cycle, absent estrus, absent long term depression, adipose tissue inflammation, adipose tissue phenotype, anovulation, behavior/neurological phenotype, cardiac ischemia, constricted vagina orifice, decreased CD4-positive, alpha beta T cell number, decreased CD8-positive, naive alpha-beta T cell number, decreased T cell proliferation, decreased body length, decreased bone mineral content, decreased carbon dioxide production, decreased cardiac muscle contractility, decreased cardiac output, decreased cell death, decreased circulating adiponectin level, decreased circulating adrenaline level, decreased circulating glucose level, decreased circulating growth hormone level, decreased circulating noradrenaline level, decreased circulating thyroxine level, decreased core body temperature, decreased corpora lutea number, decreased energy expenditure, decreased exploration in new environment, decreased follicle stimulating hormone level, decreased gonadal fat pad weight, decreased heart weight, decreased insulin secretion, decreased lean body mass, decreased liver triglyceride level, decreased locomotor activity, decreased mature ovarian follicle number, decreased motor neuron number, decreased muscle weight, decreased oocyte number, decreased oxygen consumption, decreased prostaglandin level, decreased pulmonary ventilation, decreased respiratory quotient, decreased response to antigen, decreased somatotroph cell number, decreased spleen weight, decreased splenocyte number, decreased systemic arterial blood pressure, decreased systemic arterial systolic blood pressure, decreased urine albumin level, decreased uterus weight, degranulated pancreatic beta cells, delayed estrous cycle, delayed wound healing, endocrine/exocrine gland phenotype, extended life span, growth/size/body region phenotype, homeostasis/metabolism phenotype, impaired adaptive thermogenesis, impaired balance, impaired righting response, improved glucose tolerance, increased anxiety-related response, increased birth weight, increased body fat mass, increased body length, increased body size, increased bone volume, increased brown adipose tissue amount, increased carbon dioxide production, increased cholesterol level, increased circulating alanine transaminase level, increased circulating alkaline phosphatase level, increased circulating aspartate transaminase level, increased circulating fructosamine level, increased circulating glucose level, increased circulating interleukin-6 level, increased circulating iron level, increased circulating ketone body level, increased creatinine clearance, increased effector memory CD4-positive, alpha-beta T cell number, increased effector memory CD8-positive, alpha-beta T cell number, increased enterocyte apoptosis, increased epididymal fat pad weight, increased exploration in new environment, increased food intake, increased glucagon secretion, increased gonadal fat pad weight, increased hepatocyte apoptosis, increased insulin secretion, increased insulin sensitivity, increased interleukin-6 secretion, increased kidney weight, increased lean body mass, increased left ventricle diastolic pressure, increased liver triglyceride level, increased liver weight, increased mean systemic arterial blood pressure, increased mesenteric fat pad weight, increased metastatic potential, increased neutrophil cell number, increased omental fat pad weight, increased oxygen consumption, increased pancreatic alpha cell number, increased pancreatic beta cell mass, increased pancreatic beta cell number, increased pancreatic islet cell apoptosis, increased percent body fat/body weight, increased respiratory quotient, increased sensitivity to induced morbidity/mortality, increased subcutaneous adipose tissue amount, increased susceptibility to age related obesity, increased susceptibility to autoimmune diabetes, increased susceptibility to diet-induced obesity, increased susceptibility to endotoxin shock, increased susceptibility to non-insulin-dependent diabetes, increased susceptibility to parasitic infection, increased susceptibility to weight gain, increased total body fat amount, increased vasoconstriction, lethality, incomplete penetrance, limb grasping, macrovesicular hepatic steatosis, maternal effect, microvesicular hepatic steatosis, nervous system phenotype, no abnormal phenotype detected, pancreatic islet hyperplasia, periinsulitis, premature death, reduced female fertility, reduced long term potentiation, reduced male fertility, reduced male mating frequency, renal glomerular immunoglobulin deposits, renal glomerular protein deposits, reproductive system phenotype, short tail, skeleton phenotype, small male preputial glands, small seminal vesicle, small uterus, trunk curl