Monarch Ortholog Phenotypes
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Mouse (31 sources):
abnormal NK cell differentiation,
abnormal aorta endothelium morphology,
abnormal aorta smooth muscle morphology,
abnormal artery morphology,
abnormal axon morphology,
abnormal diencephalon morphology,
abnormal leukocyte migration,
abnormal limb morphology,
abnormal lymphocyte physiology,
abnormal pericardial cavity morphology,
abnormal pericyte morphology,
abnormal telencephalon morphology,
abnormal vascular branching morphogenesis,
abnormal vascular endothelial cell morphology,
abnormal vascular smooth muscle morphology,
abnormal visceral yolk sac morphology,
decreased physiological sensitivity to xenobiotic,
decreased susceptibility to experimental autoimmune encephalomyelitis,
embryonic lethality during organogenesis, complete penetrance,
enlarged pericardium,
immune system phenotype,
impaired fibroblast cell migration,
increased CD4-positive, alpha beta T cell number,
increased CD8-positive, alpha-beta T cell number,
increased neuron apoptosis,
increased vascular endothelial cell apoptosis,
lethality throughout fetal growth and development, complete penetrance,
no abnormal phenotype detected,
pericardial edema,
poor arterial differentiation,
vascular smooth muscle hypoplasia
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