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Summary Expression Phenotypes Gene Literature (96) GO Terms (10) Nucleotides (187) Proteins (62) Interactants (295) Wiki

cdc45     cell division cycle 45

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: cdc45 assayed (1 source)
Computed annotations: cdc45 assayed (2 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (80 sources): 2-3 toe syndactyly, Abnormal rib morphology, Abnormality of epiphysis morphology, Abnormality of the outer ear, Anal atresia, Anal stenosis, Anotia, Aplasia/Hypoplasia of the patella, Aplastic clavicle, Atresia of the external auditory canal, [+]
Mouse (4 sources): absent inner cell mass proliferation, embryonic lethality between implantation and somite formation, complete penetrance, no abnormal phenotype detected, preweaning lethality, complete penetrance

View all ortholog results at Monarch