agr2 Phenotypes

Phenotypes

XB-GENEPAGE-971547

Gene Symbol: agr2 Gene Name: anterior gradient 2, protein disulphide isomerase family member

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: agr2 assayed (22 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (21 sources): abnormal Peyer's patch follicle morphology, abnormal enterocyte morphology, abnormal enterocyte proliferation, abnormal gastric chief cell morphology, abnormal gastric parietal cell morphology, abnormal intestinal goblet cell morphology, abnormal intestinal mucosa morphology, abnormal intestine physiology, abnormal large intestine crypts of Lieberkuhn morphology, abnormal respiratory system development, abnormal stomach enteroendocrine cell morphology, abnormal stomach glandular epithelium morphology, decreased total fat pad weight, enlarged stomach, ileum inflammation, increased Paneth cell number, increased cell proliferation, increased enterocyte apoptosis, increased susceptibility to induced colitis, premature death, stomach mucosa hyperplasia [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (21 sources): abnormal Peyer's patch follicle morphology, abnormal enterocyte morphology, abnormal enterocyte proliferation, abnormal gastric chief cell morphology, abnormal gastric parietal cell morphology, abnormal intestinal goblet cell morphology, abnormal intestinal mucosa morphology, abnormal intestine physiology, abnormal large intestine crypts of Lieberkuhn morphology, abnormal respiratory system development, [+]