| Monarch Ortholog Phenotypes
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Human (13 sources):
Anemia,
Chronic kidney disease,
Cognitive impairment,
Focal segmental glomerulosclerosis,
Gout,
Hyperuricemia,
Intrauterine growth retardation,
Nephropathy,
Neutropenia,
Recurrent infections,
[+]
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Mouse (14 sources):
abnormal pancreatic beta cell morphology,
abnormal pancreatic beta cell physiology,
abnormal pancreatic delta cell morphology,
decreased body size,
decreased lean body mass,
decreased skeletal muscle mass,
endocrine/exocrine gland phenotype,
homeostasis/metabolism phenotype,
increased hepatocyte apoptosis,
increased hepatocyte proliferation,
[+]
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.