Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (5) GO Terms (3) Nucleotides (929) Proteins (59) Interactants (295) Wiki

sec61a1     Sec61 translocon alpha 1 subunit

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: sec61a1 assayed (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (13 sources): Anemia, Chronic kidney disease, Cognitive impairment, Focal segmental glomerulosclerosis, Gout, Hyperuricemia, Intrauterine growth retardation, Nephropathy, Neutropenia, Recurrent infections, [+]
Mouse (14 sources): abnormal pancreatic beta cell morphology, abnormal pancreatic beta cell physiology, abnormal pancreatic delta cell morphology, decreased body size, decreased lean body mass, decreased skeletal muscle mass, endocrine/exocrine gland phenotype, homeostasis/metabolism phenotype, increased hepatocyte apoptosis, increased hepatocyte proliferation, [+]

View all ortholog results at Monarch