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XB-GENEPAGE-966538
adam11 ADAM metallopeptidase domain 11
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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| increased size of the cranial neural crest (4 sources), abnormal neural tube closure (3 sources), abnormal cell migration in neural crest (2 sources), increased cell population proliferation (2 sources), abnormal branchial crest (1 source), decreased cell migration in branchial crest (1 source), decreased cell migration in cranial neural crest (1 source) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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| Manual annotations: adam11 manipulated (8 sources) |
| Computed annotations: adam11 assayed (1 source) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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| Xla Wt + adam11 MO (unilateral) (5 sources), Xla Wt + adam11 MO (2 sources), Xla Wt + adam11 MO + cranial neural crest transplant (2 sources), Xla Wt + adam11 + animal cap explant + dissociation (1 source), Xla Wt + adam11 MO (1 source), Xla Wt + adam11 MO + cnc explant + fibronectin (1 source), Xla Wt + adam11 MO + MbC (1 source), Xla wt + adam11 MO + MbC + CMV reporter (1 source) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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| Mouse (1 source): abnormal spatial learning |