cnr1 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-962200

Gene Symbol: cnr1 Gene Name: cannabinoid receptor 1 (brain)

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
decreased size of the eye (2 sources)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: cnr1 manipulated (4 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + cnr1 MO (5 sources), Xla Wt + cnr1 MO (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (68 sources): abnormal active avoidance behavior, abnormal axon fasciculation, abnormal cerebral cortex morphology, abnormal craniofacial morphology, abnormal cued conditioning behavior, abnormal depression-related behavior, abnormal embryo size, abnormal excitatory postsynaptic potential, abnormal food intake, abnormal gastrointestinal motility, abnormal impulsive behavior control, abnormal inhibitory postsynaptic currents, abnormal learning/memory/conditioning, abnormal locomotor activation, abnormal nervous system development, abnormal neuron physiology, abnormal neuronal precursor proliferation, abnormal paired-pulse facilitation, abnormal response to novel object, abnormal sweet taste sensitivity, abnormal synaptic plasticity, absent long term depression, behavior/neurological phenotype, catalepsy, decreased chemically-elicited antinociception, decreased circulating progesterone level, decreased exploration in new environment, decreased locomotor activity, decreased percent body fat/body weight, decreased survivor rate, decreased susceptibility to diet-induced obesity, decreased synaptic depression, decreased vertical activity, early parturition, enhanced long term potentiation, growth/size/body region phenotype, homeostasis/metabolism phenotype, hypoalgesia, impaired behavioral response to addictive substance, impaired behavioral response to morphine, impaired behavioral response to xenobiotic, impaired conditioned place preference behavior, impaired cued conditioning behavior, increased aggression towards mice, increased anxiety-related response, increased behavioral withdrawal response, increased cerebral infarct size, increased chemical nociceptive threshold, increased chemically-elicited antinociception, increased circulating estradiol level, increased exploration in new environment, increased follicle stimulating hormone level, increased insulin sensitivity, increased physiological sensitivity to xenobiotic, increased sensitivity to induced morbidity/mortality, increased sensitivity to xenobiotic induced morbidity/mortality, increased susceptibility to ischemic brain injury, increased susceptibility to neuronal excitotoxicity, increased susceptibility to pharmacologically induced seizures, increased thermal nociceptive threshold, maternal effect, nervous system phenotype, no abnormal phenotype detected, postnatal lethality, incomplete penetrance, premature death, preweaning lethality, incomplete penetrance, reduced long term depression, skeleton phenotype [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (68 sources): abnormal active avoidance behavior, abnormal axon fasciculation, abnormal cerebral cortex morphology, abnormal craniofacial morphology, abnormal cued conditioning behavior, abnormal depression-related behavior, abnormal embryo size, abnormal excitatory postsynaptic potential, abnormal food intake, abnormal gastrointestinal motility, [+]