itga8 Phenotypes

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Phenotypes

Gene Literature (1)

Nucleotides (109)

Interactants (20)

XB-GENEPAGE-961824

Gene Symbol: itga8 Gene Name: integrin subunit alpha 8

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: itga8 assayed (3 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (28 sources): Abnormal cardiovascular system morphology, Abnormal foot morphology, Abnormal intestine morphology, Abnormal morphology of female internal genitalia, Abnormal sacrum morphology, Bicornuate uterus, Cleft palate, Depressed nasal ridge, Epicanthus, Fetal polyuria, Hypertelorism, Hypertension, Low-set ears, Non-midline cleft of the upper lip, Nonketotic hypoglycemia, Oligohydramnios, Potter facies, Primary amenorrhea, Proteinuria, Pulmonary hypoplasia, Renal agenesis, Renal dysplasia, Retrognathia, Sirenomelia, Talipes equinovarus, Tracheoesophageal fistula, Urogenital fistula, Vaginal atresia [+]
Mouse (30 sources): abnormal branching involved in lung morphogenesis, abnormal cell adhesion, abnormal cell migration, abnormal circulating calcium level, abnormal circulating sodium level, abnormal kidney development, abnormal kidney morphology, abnormal lung saccule morphology, abnormal pulmonary elastic fiber morphology, abnormal ureter development, abnormal ureteric bud invasion, abnormal vestibular hair cell stereociliary bundle morphology, absent ureter, adhesive atelectasis, behavior/neurological phenotype, decreased circulating glucose level, decreased vestibular hair cell stereocilia number, dilated respiratory conducting tube, fused right lung lobes, fused vestibular hair cell stereocilia, impaired branching involved in ureteric bud morphogenesis, impaired lung lobe morphogenesis, impaired synaptic plasticity, increased thigmotaxis, increased total body fat amount, postnatal lethality, incomplete penetrance, preweaning lethality, incomplete penetrance, reduced long term potentiation, renal/urinary system phenotype, small kidney [+]
View all ortholog results at Monarch