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XB-GENEPAGE-957719
itk IL2-inducible T cell kinase
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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Human (13 sources): Anemia, Autoimmunity, Decreased circulating IgG level, Elevated erythrocyte sedimentation rate, Hepatomegaly, Lymphadenopathy, Lymphoma, Pancytopenia, Recurrent aphthous stomatitis, Recurrent infections, [+] |
Mouse (32 sources): abnormal CD4-positive, alpha-beta T cell physiology, abnormal CD8-positive, alpha-beta T cell differentiation, abnormal CD8-positive, alpha-beta T cell physiology, abnormal NK T cell morphology, abnormal T cell activation, abnormal cell proliferation, abnormal gamma-delta T cell morphology, abnormal positive T cell selection, abnormal thymus cell ratio, decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number, [+] |
View all ortholog results at Monarch |