tbx4 Phenotypes

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Phenotypes

Gene Literature (10)

Nucleotides (57)

Interactants (175)

XB-GENEPAGE-951381

Gene Symbol: tbx4 Gene Name: T-box 4

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal hindlimb (2 sources), abnormal joint region morphology (1 source), abnormally decreased number of hindlimb digit (1 source), decreased length of femur (1 source), decreased size of the hindlimb (1 source)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xtr.wt +tbx4 CRISPR (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (33 sources): Abnormal cardiac septum morphology, Abnormality of epiphysis morphology, Abnormality of pelvic girdle bone morphology, Abnormality of the knee, Acromelia of the lower limbs, Amelia, Amelia involving the upper limbs, Aplasia/Hypoplasia of the lungs, Aplasia/Hypoplasia of the patella, Cleft palate, Coxa vara, Cryptorchidism, Flat capital femoral epiphysis, Full cheeks, High palate, Hip dysplasia, Hypoplasia of penis, Hypoplasia of the lesser trochanter, Micrognathia, Non-midline cleft of the upper lip, Orofacial cleft, Patellar aplasia, Patellar dislocation, Patellar hypoplasia, Pes planus, Polyhydramnios, Sandal gap, Short femur, Short stature, Small scrotum, Talocalcaneal synostosis, Tarsal synostosis, Wide capital femoral epiphyses [+]
Mouse (29 sources): abnormal allantois morphology, abnormal embryo size, abnormal forebrain development, abnormal hindbrain development, abnormal hindlimb morphology, abnormal ischium morphology, abnormal limb bud morphology, abnormal limb development, abnormal midbrain development, abnormal patella morphology, abnormal umbilical artery morphology, abnormal vascular regression, absent umbilical cord, delayed allantois development, delayed chorioallantoic fusion, distended pericardium, embryonic lethality during organogenesis, complete penetrance, embryonic lethality during organogenesis, incomplete penetrance, embryonic lethality prior to tooth bud stage, failure of chorioallantoic fusion, fused phalanges, increased allantois apoptosis, increased respiratory quotient, limbs/digits/tail phenotype, no abnormal phenotype detected, pericardial edema, preweaning lethality, complete penetrance, small allantois, small hindlimb buds [+]
View all ortholog results at Monarch