afdn Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-948332

Gene Symbol: afdn Gene Name: afadin, adherens junction formation factor

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (44 sources): abnormal amniotic cavity morphology, abnormal cerebral cortex morphology, abnormal cortical ventricular zone morphology, abnormal ectoderm development, abnormal embryo turning, abnormal embryonic neuroepithelium morphology, abnormal excitatory postsynaptic potential, abnormal extraembryonic coelom morphology, abnormal germ layer development, abnormal hindbrain development, abnormal hippocampus CA1 region morphology, abnormal hippocampus pyramidal cell morphology, abnormal limb bud morphology, abnormal mesoderm development, abnormal neocortex morphology, abnormal nervous system tract morphology, abnormal optic vesicle formation, abnormal prepulse inhibition, abnormal radial glial cell morphology, abnormal rostral-caudal body axis extension, abnormal somite development, abnormal startle reflex, abnormal stratification in cerebral cortex, abnormal synapse morphology, abnormal telencephalon development, abnormal uterus morphology, absent allantois, absent heart, absent neural folds, absent notochord, absent somites, decreased embryo size, decreased prepulse inhibition, ectopic hippocampus pyramidal cells, ectopic neuron, embryonic growth arrest, embryonic lethality during organogenesis, complete penetrance, increased brain size, increased neocortex size, increased neuronal precursor cell number, increased radial glial cell number, preweaning lethality, complete penetrance, small spleen, thin cortical plate [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (44 sources): abnormal amniotic cavity morphology, abnormal cerebral cortex morphology, abnormal cortical ventricular zone morphology, abnormal ectoderm development, abnormal embryo turning, abnormal embryonic neuroepithelium morphology, abnormal excitatory postsynaptic potential, abnormal extraembryonic coelom morphology, abnormal germ layer development, abnormal hindbrain development, [+]