rdh10 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-944960

Gene Symbol: rdh10 Gene Name: retinol dehydrogenase 10

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal bending of tail (1 source), abnormal development of tail (1 source), abnormally posterioralized embryo (1 source), decreased size of the eye (1 source), decreased size of the head (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: rdh10 manipulated (1 source), rdh10 assayed (1 source)
Computed annotations: rdh10 assayed (2 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + aldh1a2 MO + rdh10 MO (1 source), Xla Wt + rdh10 MO (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (83 sources): abnormal cardiac outflow tract development, abnormal cerebral cortex morphology, abnormal cranial ganglia morphology, abnormal craniofacial development, abnormal craniofacial morphology, abnormal digit development, abnormal dorsal aorta morphology, abnormal embryo development, abnormal embryo turning, abnormal embryonic tissue morphology, abnormal eye development, abnormal forelimb bud morphology, abnormal forelimb morphology, abnormal fourth pharyngeal arch morphology, abnormal frontonasal prominence morphology, abnormal geniculate ganglion morphology, abnormal glossopharyngeal ganglion morphology, abnormal heart development, abnormal heart looping, abnormal heart tube morphology, abnormal hindbrain development, abnormal lateral nasal prominence morphology, abnormal limb morphology, abnormal lung development, abnormal maxillary prominence morphology, abnormal medial nasal prominence morphology, abnormal mesoderm development, abnormal metanephros morphology, abnormal midgut morphology, abnormal nasal placode morphology, abnormal optic vesicle formation, abnormal otic vesicle development, abnormal otic vesicle morphology, abnormal reproductive system development, abnormal rostral-caudal body axis extension, abnormal second pharyngeal arch artery morphology, abnormal seminiferous tubule morphology, abnormal sixth pharyngeal arch morphology, abnormal spermatogonia morphology, abnormal third pharyngeal arch morphology, abnormal trigeminal ganglion morphology, abnormal vagus ganglion morphology, abnormal vestibulocochlear ganglion morphology, absent cornea, absent fourth pharyngeal arch, absent lung buds, absent lungs, absent nasal cavity, absent pharyngeal arches, absent sixth pharyngeal arch, absent sixth pharyngeal arch artery, absent third pharyngeal arch, absent third pharyngeal arch artery, arrest of male meiosis, cardiac edema, caudal body truncation, circling, decreased embryo size, decreased somite size, decreased testis weight, decreased ventral retina size, embryo phenotype, embryo tissue necrosis, embryonic growth arrest, embryonic growth retardation, embryonic lethality during organogenesis, complete penetrance, failure of heart looping, frontonasal prominence hypoplasia, fused pharyngeal arches, impaired branching involved in trachea morphogenesis, incomplete embryo turning, lethality during fetal growth through weaning, complete penetrance, liver hypoplasia, nervous system phenotype, no abnormal phenotype detected, reduced male fertility, reproductive system phenotype, seminiferous tubule degeneration, small forelimb buds, small liver, small otic vesicle, small stomach, thin cerebral cortex [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (83 sources): abnormal cardiac outflow tract development, abnormal cerebral cortex morphology, abnormal cranial ganglia morphology, abnormal craniofacial development, abnormal craniofacial morphology, abnormal digit development, abnormal dorsal aorta morphology, abnormal embryo development, abnormal embryo turning, abnormal embryonic tissue morphology, [+]