| Monarch Ortholog Phenotypes
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Human (28 sources):
Abnormal foot morphology,
Abnormality of metabolism/homeostasis,
Abnormality of the hand,
Axonal regeneration,
Cholecystitis,
Cholelithiasis,
Constriction of peripheral visual field,
Decreased motor nerve conduction velocity,
Decreased number of large peripheral myelinated nerve fibers,
Difficulty walking,
Distal muscle weakness,
Hyperbilirubinemia,
Hyporeflexia,
Jaundice,
Macular atrophy,
Nonspherocytic hemolytic anemia,
Normochromic anemia,
Normocytic anemia,
Nyctalopia,
Optic disc pallor,
Paralysis,
Peripheral hypomyelination,
Peripheral neuropathy,
Photophobia,
Reduced visual acuity,
Reticulocytosis,
Scoliosis,
Splenomegaly
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Mouse (11 sources):
abnormal erythropoiesis,
decreased body size,
decreased erythrocyte cell number,
decreased hematocrit,
decreased hemoglobin content,
decreased mean corpuscular hemoglobin,
hyperchromasia,
increased kidney iron level,
increased spleen red pulp amount,
increased spleen weight,
[+]
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.