gmds Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-943014

Gene Symbol: gmds Gene Name: GDP-mannose 4,6-dehydratase

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: gmds assayed (11 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (48 sources): abnormal body length, abnormal circulating alkaline phosphatase level, abnormal circulating chloride level, abnormal circulating iron level, abnormal cranium morphology, abnormal erythrocyte cell number, abnormal hematocrit, abnormal hemoglobin content, abnormal snout morphology, decreased CD4-positive NK T cell number, decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number, decreased CD4-positive, alpha beta T cell number, decreased CD8-positive, naive alpha-beta T cell number, decreased KLRG1+ CD8 alpha beta T cell number, decreased KLRG1-positive NK cell number, decreased Ly6C-positive mature NK cell number, decreased T-helper cell number, decreased alpha-beta T cell number, decreased body length, decreased bone mineral content, decreased circulating glucose level, decreased dendritic cell number, decreased effector memory CD8-positive, alpha-beta T cell number, decreased erythrocyte cell number, decreased hematocrit, decreased hemoglobin content, decreased lean body mass, decreased macrophage cell number, decreased mature NK cell number, decreased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number, decreased memory-marker CD4-negative NK T cell number, decreased memory-marker CD4-positive NK T cell number, decreased plasmacytoid dendritic cell number, decreased regulatory T cell number, decreased transitional stage T2 B cell number, increased CD4-negative NK T cell number, increased CD4-positive, alpha beta T cell number, increased CD8-positive, alpha-beta T cell number, increased Ly6C-positive NK T cell number, increased NK T cell number, increased circulating alkaline phosphatase level, increased circulating iron level, increased gamma-delta T cell number, increased granulocyte number, increased immature NK cell number, increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number, increased memory-marker NK cell number, increased neutrophil cell number [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (48 sources): abnormal body length, abnormal circulating alkaline phosphatase level, abnormal circulating chloride level, abnormal circulating iron level, abnormal cranium morphology, abnormal erythrocyte cell number, abnormal hematocrit, abnormal hemoglobin content, abnormal snout morphology, decreased CD4-positive NK T cell number, [+]