| Monarch Ortholog Phenotypes
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Human (12 sources):
Cataract,
Chorioretinal atrophy,
Exudative vitreoretinopathy,
Glaucoma,
Myopia,
Optic atrophy,
Optically empty vitreous,
Peripheral tractional retinal detachment,
Retinal pigment epithelial atrophy,
Visual field defect,
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Mouse (18 sources):
abnormal axon morphology,
abnormal chondrocyte physiology,
abnormal heart development,
abnormal phalanx morphology,
absent atrioventricular cushions,
absent conotruncal ridges,
decreased atrioventricular cushion size,
decreased embryo size,
decreased fetal size,
dilated heart,
dilated heart atrium,
dilated heart left ventricle,
embryonic lethality during organogenesis, complete penetrance,
embryonic lethality during organogenesis, incomplete penetrance,
neonatal lethality, complete penetrance,
nervous system phenotype,
no abnormal phenotype detected,
preweaning lethality, complete penetrance
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.