ctnnd1 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-919826

Gene Symbol: ctnnd1 Gene Name: catenin delta 1

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal heart looping (2 sources), dead whole organism (2 sources), abnormal cement gland (1 source), abnormal craniofacial region morphology (1 source), abnormal m. rectus abdominis morphology (1 source), abnormal myofibril morphology (1 source), abnormally delayed closure of blastopore (1 source), decreased size of the branchial arch skeleton (1 source), decreased size of the craniofacial skeleton (1 source), decreased size of the head (1 source), decreased size of the heart (1 source), decreased size of the mouth (1 source)

Anatomical Phenotypes

Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.

abnormal heart looping (2 sources), dead whole organism (2 sources), abnormal cement gland (1 source), abnormal craniofacial region morphology (1 source), abnormal m. rectus abdominis morphology (1 source), abnormal myofibril morphology (1 source), abnormally delayed closure of blastopore (1 source), decreased size of the branchial arch skeleton (1 source), decreased size of the craniofacial skeleton (1 source), decreased size of the head (1 source), decreased size of the heart (1 source), decreased size of the mouth (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: ctnnd1 manipulated (2 sources), ctnnd1 assayed (1 source)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xtr Wt + ctnnd1 CRISPR (8 sources), Xtr Wt + ctnnd1 CRISPR (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (20 sources): Abnormal eyelid morphology, Abnormal hair quantity, Abnormality of the orbital region, Abnormality of vision, Anal atresia, Bilateral cleft lip and palate, Carious teeth, Conductive hearing impairment, Conical tooth, Cutaneous syndactyly, Distichiasis, Ectropion of lower eyelids, Epidermoid cyst, Euryblepharon, Facial asymmetry, Finger syndactyly, Flat face, High forehead, Hypertelorism, Tooth agenesis [+]
Mouse (30 sources): abnormal cell adhesion, abnormal hippocampus CA1 region morphology, abnormal hippocampus pyramidal cell morphology, abnormal kidney development, abnormal major salivary gland morphology, abnormal metanephros morphology, abnormal mitosis, abnormal mitotic spindle morphology, abnormal podocyte morphology, abnormal proximal convoluted tubule morphology, abnormal renal glomerulus morphology, abnormal renal tubule epithelial cell primary cilium morphology, abnormal sublingual gland morphology, abnormal submandibular gland morphology, abnormal submandibular gland physiology, binucleate, decreased cell proliferation, decreased renal glomerulus number, dilated distal convoluted tubule, dilated proximal convoluted tubule, epidermal hyperplasia, increased kidney apoptosis, increased kidney cell proliferation, increased skin tumor incidence, increased submandibular gland apoptosis, neonatal lethality, complete penetrance, postnatal lethality, complete penetrance, renal/urinary system phenotype, retarded hair growth, small kidney [+]
View all ortholog results at Monarch