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Summary Expression Phenotypes Gene Literature (61) GO Terms (9) Nucleotides (117) Proteins (40) Interactants (421) Wiki
XB-GENEPAGE-868376

nanos1     nanos homolog 1

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
absent primordial germ cell (2 sources), abnormal RNA polymerase II activity (1 source), abnormal cell migration (1 source), abnormally decreased number of germ cell (1 source), increased apoptosis in primordial germ cell (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: nanos1 manipulated (2 sources)
Computed annotations: nanos1 assayed (7 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + nanos1 MO (6 sources), Xla Wt + nanos1 MO (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (12 sources): Abnormal male germ cell morphology, Abnormal sperm morphology, Abnormal sperm tail morphology, Abnormal spermatogenesis, Azoospermia, Decreased testicular size, Globozoospermia, Increased circulating gonadotropin level, Infertility, Non-obstructive azoospermia, [+]
Mouse (1 source): no abnormal phenotype detected

View all ortholog results at Monarch